A review of “The Knowledge Machine”

https://science.sciencemag.org/content/371/6524/37 Science’s irrational origins Itai Yanai, Martin J. Lercher What is the scientific method, and what makes it the most efficient approach for generating insight? In┬áThe Knowledge Machine, Michael Strevens argues that to answer this question, we must acknowledge the role played by the undisciplined and emotional nature of the humans who carry it out.…

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Separating the signal from the noise in scRNA-Seq data (new paper!)

We’ve developed a smoothing algorithm that makes the analysis of high-throughput single-cell RNA-Seq a lot easier. The algorithm effectively removes technical noise while largely preserving biological heterogeneity. You can read the paper on bioRxiv and find reference implementations in Python/R/Matlab on github. In the YanaiLab, we love single-cell RNA-Seq data, and we’re proud of our…

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