https://science.sciencemag.org/content/371/6524/37 Science’s irrational origins Itai Yanai, Martin J. Lercher What is the scientific method, and what makes it the most efficient approach for generating insight? In The Knowledge Machine, Michael Strevens argues that to answer this question, we must acknowledge the role played by the undisciplined and emotional nature of the humans who carry it out.…
We’ve developed a smoothing algorithm that makes the analysis of high-throughput single-cell RNA-Seq a lot easier. The algorithm effectively removes technical noise while largely preserving biological heterogeneity. You can read the paper on bioRxiv and find reference implementations in Python/R/Matlab on github. In the YanaiLab, we love single-cell RNA-Seq data, and we’re proud of our…
Read more Separating the signal from the noise in scRNA-Seq data (new paper!)
